Basic Information

Gene symbol CD7 Synonyms GP40, LEU-9, TP41, Tp40 Type of gene protein-coding
Description CD7 molecule

GTO ID GTC3032
Trial ID NCT05377827
Disease Adult T-Cell Leukemia/Lymphoma | Angioimmunoblastic T-Cell Lymphoma | Anaplastic Large Cell Lymphoma | T-Cell Prolymphocytic Leukemia | Peripheral T-Cell Lymphoma | T-Cell Non-Hodgkin's Lymphoma | Nasal Type Extranodal NK/T-Cell Lymphoma | Mycosis Fungoides | Primary Cutaneous Gamma-Delta T-Cell Lymphoma | Hepatosplenic T-Cell Lymphoma | Sezary's Disease
Altered gene CD7
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD7 CAR-T cells
PhasePhase1
Recruitment statusNot Recruiting
TitleDose-Escalation and Dose-Expansion Study to Evaluate the Safety and Tolerability of Anti-CD7 Allogeneic CAR T-Cells (WU-CART-007) in Patients With CD7+ Hematologic Malignancies
Year2022
CountryUnited States
Company sponsorWashington University School of Medicine
Other ID(s)22-x081

Clinical Result

Cohort 1
Administration route None
Donor type Allogeneic
Pts 48
Age Adult, Older_Adult
Lymph depletion Yes

Relationship Graph

Overview of Knowledge Graph