Basic Information

Gene symbol MSLN Synonyms MPF, SMRP Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description mesothelin

GTO ID GTC3030
Trial ID NCT05373147
Disease Solid Tumor
Altered gene MSLN
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment MSLN CAR-T cells
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleαPD1-MSLN-CAR T Cells for the Treatment of MSLN-positive Advanced Solid Tumors
Year2022
CountryChina
Company sponsorShanghai Mengchao Cancer Hospital
Other ID(s)BZDS1901

Clinical Result

Cohort 1
Administration route None
Dosage 1E5 cells/kg, 3E5 cells/kg, 1E6 cells/kg, 3E6 cells/kg
Donor type Autologous
Pts 21
Age Adult, Older_Adult

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