Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3028
Trial ID NCT05371093
Disease Follicular Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment YesCAR-Ta|Axicabtagene Ciloleucel|axi-cel
Generation2nd
PhasePhase3
Recruitment statusRecruiting
TitleStudy of Axicabtagene Ciloleucel Versus Standard of Care Therapy in Participants With Relapsed/Refractory Follicular Lymphoma
Year2022
CountryUnited Kingdom
Company sponsorKite, A Gilead Company
Other ID(s)KT-US-473-0133|2021-003260-28
Vector information
Vectorlentivirus
ConstructscFv-CD28-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 2E6 cells/kg, single infusion
Donor type Autologous
Pts 230
Age Adult, Older_Adult
Lymph depletion Yes

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