Basic Information

Gene symbol S Synonyms E2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description spike glycoprotein

GTO ID GTC3025
Trial ID NCT05367843
Disease COVID-19
Altered gene S
Therapeutic/Target gene Therapeutic gene
TherapymRNA vaccine
Treatment PRIME-2-CoV_Beta
PhasePhase1
Recruitment statusCompleted
TitleA Phase 1, Dose Ranging Study Assessing the Safety, Tolerability, Immunogenicity of Vaccine Candidate PRIME-2-CoV_Beta, Orf Virus Expressing SARS-CoV-2 Spike and Nucleocapsid Proteins (ORFEUS Study)
Year2022
CountryUnited States|Germany
Company sponsorSperansa Therapeutics
Other ID(s)D1701-VrV-101|2021-005219-30

Clinical Result

Cohort1: Pre-vaccinated
Administration route intramuscular injection
Age Adult, Older_Adult
Cohort2: Vaccine-naïve
Administration route intramuscular injection
Age Adult, Older_Adult

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