Basic Information

Gene symbol CD276 Synonyms 4Ig-B7-H3, B7-H3, B7H3, B7RP-2 Type of gene protein-coding
Description CD276 molecule

GTO ID GTC3023
Trial ID NCT05366179
Disease Brain Glioblastoma Multiforme
Altered gene CD276
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CAR.B7-H3T cells
PhasePhase1
Recruitment statusRecruiting
TitleAutologous CAR-T Cells Targeting B7-H3 in Recurrent or Refractory GBM CAR.B7-H3Tc
Year2022
CountryUnited States
Company sponsorUNC Lineberger Comprehensive Cancer Center
Other ID(s)LCCC2059-ATL

Clinical Result

Cohort 1
Administration route intraventricular infusion
Dosage 2E6 cells/infusion
Donor type Autologous
Pts 36
Age Adult, Older_Adult

Relationship Graph

Overview of Knowledge Graph