Basic Information

Gene symbol MS4A1 Synonyms B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 Type of gene protein-coding
Description membrane spanning 4-domains A1

GTO ID GTC3022
Trial ID NCT05360238
Disease Diffuse Large B-Cell Lymphoma | Small Lymphocytic Lymphoma | B-Cell Lymphoma | B-Cell Non-Hodgkin's Lymphoma | Mantle Cell Lymphoma | Chronic Lymphocytic Leukemia
Altered gene CD20
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment MB-106
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleStudy to Assess Safety, Tolerability and Efficacy of MB-106 in Patients With Relapsed or Refractory B-Cell NHL or CLL
Year2022
CountryUnited States
Company sponsorMustang Bio
Other ID(s)MB106-CD20-001|1R44CA265616-01

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 3.3E7 cells/kg
Donor type Autologous
Pts 287
Age Adult, Older_Adult

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