Basic Information

Gene symbol FOLH1 Synonyms FGCP, FOLH, GCP2, GCPII, NAALAD1, PSM, PSMA, mGCP Type of gene protein-coding
Description folate hydrolase 1

GTO ID GTC3017
Trial ID NCT05354375
Disease Castration-Resistant Prostate Cancer
Altered gene PSMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment PSMA CAR-T cells
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleClinical Study of PSMA-targeted CAR-T Cells in the Treatment of Castration-resistant Prostate Cancer
Year2022
CountryChina
Company sponsorThe Affiliated Hospital of Xuzhou Medical University
Other ID(s)XYFY2021-KL172-02

Clinical Result

Cohort1: Phase 1
Administration route None
Dosage 1E8 cells/person, 1E9 cells/person, 1E10/person
Pts 9
Age Adult, Older_Adult
Lymph depletion Yes
Cohort2: Phase 2
Administration route None
Pts 11
Age Adult, Older_Adult
Lymph depletion Yes

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