Basic Information

Gene symbol CD70 Synonyms CD27-L, CD27L, CD27LG, LPFS3, TNFSF7, TNLG8A Type of gene protein-coding
Description CD70 molecule

GTO ID GTC3015
Trial ID NCT05353530
Disease Glioblastoma
Altered gene CD70
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment 8R-70CAR
PhasePhase1
Recruitment statusNot Recruiting
TitlePhase I Study of IL-8 Receptor-modified CD70 CAR T Cell Therapy in CD70+ and MGMT-unmethylated Adult Glioblastoma (IMPACT)
Year2022
CountryUnited States
Company sponsorUniversity of Florida
Other ID(s)IRB202200057

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E6 cells/kg, 1E7 cells/kg, 1E8 cells/kg
Donor type Autologous
Pts 18
Age Adult, Older_Adult

Relationship Graph

Overview of Knowledge Graph