Basic Information

Gene symbol TNFRSF8 Synonyms CD30, D1S166E, Ki-1 Type of gene protein-coding
Description TNF receptor superfamily member 8

GTO ID GTC3014
Trial ID NCT05352828
Disease Hodgkin's Lymphoma
Altered gene CD30
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD30 CAR-T cells
Co-treatment Nivolumab
PhasePhase1
Recruitment statusActive, Not Recruiting
TitleAutologous CD30.CAR-T in Combination With Nivolumab in cHL Patients After Failure of Frontline Therapy
Year2022
CountryUnited States
Company sponsorTessa Therapeutics
Other ID(s)TESSCAR003

Clinical Result

Cohort 1
Administration route None
Dosage 2E8 cells/m^2
Donor type Autologous
Pts 15
Age Child, Adult, Older_Adult
Lymph depletion Yes

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