Basic Information

Gene symbol PRDX2 Synonyms HEL-S-2a, NKEF-B, NKEFB, PRP, PRX2, PRXII, PTX1, TDPX1, TPX1, TSA Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description peroxiredoxin 2

GTO ID GTC3010
Trial ID NCT05349890
Disease Epithelial Cancer
Altered gene TSA
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment TSA TCR-T cells
Co-treatment CDX-1140|Pembrolizumab
PhasePhase1
Recruitment statusRecruiting
TitleA Phase I/Ib Study of Adoptively Transferred T-cell Receptor Gene-engineered T Cells (TCR-T) Targeting Patient-unique Tumor-specific Neoantigens, With in Vivo CD40 Activation and PD-1 Blockade, for Patients With Incurable Cancers
Year2022
CountryUnited States
Company sponsorProvidence Health & Services
Other ID(s)2021000572

Clinical Result

Cohort 1
Administration route infusion
Dosage 0.2~10E10 cells
Donor type autologous
Age Child, Adult, Older_Adult
Lymph depletion Yes

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