Gene symbol | PRDX2 | Synonyms | HEL-S-2a, NKEF-B, NKEFB, PRP, PRX2, PRXII, PTX1, TDPX1, TPX1, TSA | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19p13.13 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | peroxiredoxin 2 |
GTO ID | GTC3010 |
Trial ID | NCT05349890 |
Disease | Epithelial Cancer |
Altered gene | TSA |
Therapeutic/Target gene | Target gene |
Therapy | TCR-T cell |
Treatment | TSA TCR-T cells |
Co-treatment | CDX-1140|Pembrolizumab |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | A Phase I/Ib Study of Adoptively Transferred T-cell Receptor Gene-engineered T Cells (TCR-T) Targeting Patient-unique Tumor-specific Neoantigens, With in Vivo CD40 Activation and PD-1 Blockade, for Patients With Incurable Cancers |
Year | 2022 |
Country | United States |
Company sponsor | Providence Health & Services |
Other ID(s) | 2021000572 |
Cohort 1 | |||||||||||
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