Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3009
Trial ID NCT05349266
Disease Non-Hodgkin's Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment ThisCAR-T19A
Generation2nd
PhasePhase1
Recruitment statusRecruiting
TitleAssessment of Safety and Efficacy of ThisCART19A in Adult Patients With B-NHL After Failure of Autologous Chimeric Antigen Receptor T- Cell(CAR-T) Therapy
Year2022
CountryChina
Company sponsorZhejiang University
Other ID(s)FT400-003

Clinical Result

Cohort1: dose level 1
Administration route None
Dosage 2E6 cells/kg, single infusion
Donor type Allogeneic
Age Adult, Older_Adult
Lymph depletion Yes
Cohort2: dose level 2
Administration route None
Dosage 3E6 cells/kg, single infusion
Donor type Allogeneic
Age Adult, Older_Adult
Lymph depletion Yes
Cohort3: dose level 3
Administration route None
Dosage 4E6 cells/kg, single infusion
Donor type Allogeneic
Age Adult, Older_Adult
Lymph depletion Yes

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