Basic Information

Gene symbol CD276 Synonyms 4Ig-B7-H3, B7-H3, B7H3, B7RP-2 Type of gene protein-coding
Description CD276 molecule

Gene symbol EGFR Synonyms ERBB, ERBB1, ERRP, HER1, NISBD2, PIG61, mENA Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description epidermal growth factor receptor

GTO ID GTC3002
Trial ID NCT05341492
Disease Triple-Receptor Negative Breast Cancer | Lung Cancer
Altered gene EGFR|CD276
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment EGFR/B7-H3 CAR-T cells
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleEGFR/B7H3 CAR-T on Lung Cancer and Triple Negative Breast Cancer
Year2022
CountryChina
Company sponsorSecond Affiliated Hospital of Guangzhou Medical University
Other ID(s)ZZBGCART-016

Clinical Result

Cohort 1
Administration route None
Dosage 2E6 cells/kg
Pts 30
Age Adult, Older_Adult

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