Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC2994
Trial ID NCT05333302
Disease Lymphoblastic Lymphoma | B-Cell Acute Lymphoblastic Leukemia
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CAR-T cells
Co-treatment Tocilizumab
Generation2nd
PhasePhase1
Recruitment statusRecruiting
TitlePilot CAR-T Cells Therapy for Children/Young Adults With CD19+ R/R Leukemia/Lymphoma
Year2022
CountryBelarus
Company sponsorBelarusian Research Center for Pediatric Oncology, Hematology and Immunology
Other ID(s)CD19CAR-T_LL_children

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E6 cells/kg, single infusion
Donor type Autologous
Pts 10
Age Child, Adult
Lymph depletion Yes

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