Basic Information

Gene symbol CD276 Synonyms 4Ig-B7-H3, B7-H3, B7H3, B7RP-2 Type of gene protein-coding
Description CD276 molecule

GTO ID GTC2988
Trial ID NCT05323201
Disease Hepatocellular Carcinoma
Altered gene CD276
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment fhB7-H3.CAR-T cells
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleStudy Of B7-H3 CAR-T Cells in Treating Advanced Liver Cancer
Year2022
CountryChina
Company sponsorThe Affiliated Hospital of Xuzhou Medical University
Other ID(s)XYFY2021-KL272-02

Clinical Result

Cohort 1
Administration route transhepatic arterial infusion
Dosage 1E6 cells/kg, 3E6 cells/kg, 5E6 cells/kg
Pts 15
Age Adult, Older_Adult
Lymph depletion Yes

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