Basic Information

Gene symbol TNFSF13B Synonyms BAFF, BLYS, CD257, DTL, TALL-1, TALL1, THANK, TNFSF20, TNLG7A, ZTNF4 Type of gene protein-coding
Description TNF superfamily member 13b

GTO ID GTC2983
Trial ID NCT05312801
Disease B-Cell Non-Hodgkin's Lymphoma
Altered gene BAFF
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment LMY-920
PhasePhase1
Recruitment statusRecruiting
TitlePhase 1 Study of BAFF CAR-T Cells (LMY-920) for Non-Hodgkin Lymphoma
Year2022
CountryUnited States
Company sponsorLuminary Therapeutics
Other ID(s)LMY-920-001

Clinical Result

Cohort 1
Administration route None
Dosage 1E7 cells/kg, 2E7 cells/kg, 4E7 cells/kg, 8E7 cells/kg
Donor type Autologous
Pts 20
Age Adult, Older_Adult
Lymph depletion Yes

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