Basic Information

Gene symbol CTAG1B Synonyms CTAG, ESO1, CT6.1, CTAG1, LAGE-2, LAGE2B, NY-ESO-1 Type of gene protein-coding
Description cancer/testis antigen 1B

GTO ID GTC2973
Trial ID NCT05296564
Disease Bladder Urothelial Carcinoma | Mediastinum Neuroblastoma | Ovary Cancer | Lung Non-Small Cell Carcinoma | Synovial Sarcoma | Melanoma | Childhood Soft Tissue Sarcoma | Triple-Receptor Negative Breast Cancer
Altered gene NY-ESO-1
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment NY-ESO-1 TCR-T cells
HLAHLA-A*02:01|HLA-A*02:06
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleA Phase I/II Dose Escalation, Safety and Efficacy Study of Anti-NY-ESO-1 T Cell Receptor (TCR)-Gene Engineered Lymphocytes Given by Infusion to Patients With NY-ESO-1 -Expressing Metastatic Cancers
Year2022
CountryIsrael
Company sponsorHadassah Medical Organization
Other ID(s)0752-20-HMO

Clinical Result

Cohort 1
Administration route infusion
Dosage 0.1~1E10 cells
Donor type autologous
Age Adult, Older_Adult
Lymph depletion Yes

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