Basic Information

Gene symbol CLDN18 Synonyms SFTA5, SFTPJ Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description claudin 18

GTO ID GTC2962
Trial ID NCT05277987
Disease Gastroesophageal Adenocarcinoma | Pancreatic Cancer
Altered gene CLDN18
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment HEC-016
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleAn Evaluation Trial About Anti-claudin18.2 the Specificity of Chimeric Antigen Receptor T Cells in the Advanced Gastric / Esophagogastric Junction Adenocarcinoma and Pancreatic Cancer Subjects
Year2022
CountryChina
Company sponsorShenzhen Fifth People's Hospital
Other ID(s)HEC-016-GC/PC-101

Clinical Result

Cohort 1
Administration route None
Dosage 0.5E6 cells/kg, 0.5E6.5 cells/kg, 0.5E7 cells/kg
Pts 18
Age Adult, Older_Adult

Relationship Graph

Overview of Knowledge Graph