Gene symbol | AKT1 | Synonyms | AKT, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | Type of gene | protein-coding |
Chromosome | 14 | Map location | 14q32.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | AKT serine/threonine kinase 1 |
GTO ID | GTC2954 |
Trial ID | NCT05267899 |
Disease | Advanced Solid Tumor |
Altered gene | Akt-1 |
Therapeutic/Target gene | Target gene |
Therapy | ASO |
Treatment | WGI-0301 |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | A Phase I, First in Human, Open-Label, Dose-Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of WGI-0301, a Lipid Nanoparticle Suspension of Akt-1 Antisense Oligonucleotide, in Patients With Advanced Solid Tumors |
Year | 2022 |
Country | United States |
Company sponsor | Zhejiang Haichang Biotech Co., Ltd. |
Other ID(s) | WGI0301-P1U |
Vector information | |||
|
Cohort 1 | |||||
|