Basic Information

Gene symbol AKT1 Synonyms AKT, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description AKT serine/threonine kinase 1

GTO ID GTC2954
Trial ID NCT05267899
Disease Advanced Solid Tumor
Altered gene Akt-1
Therapeutic/Target gene Target gene
TherapyASO
Treatment WGI-0301
PhasePhase1
Recruitment statusRecruiting
TitleA Phase I, First in Human, Open-Label, Dose-Escalation Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of WGI-0301, a Lipid Nanoparticle Suspension of Akt-1 Antisense Oligonucleotide, in Patients With Advanced Solid Tumors
Year2022
CountryUnited States
Company sponsorZhejiang Haichang Biotech Co., Ltd.
Other ID(s)WGI0301-P1U
Vector information
VectorNo vector was used

Clinical Result

Cohort 1
Administration route None
Age Adult, Older_Adult

Relationship Graph

Overview of Knowledge Graph