Basic Information

Gene symbol CD33 Synonyms CD33rSiglec, SIGLEC-3, SIGLEC3, p67 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD33 molecule

Gene symbol COLEC10 Synonyms 3MC3, CL-10, CL-34, CLL1 Type of gene protein-coding
Description collectin subfamily member 10

GTO ID GTC2942
Trial ID NCT05248685
Disease Acute Myeloid Leukemia
Altered gene CD33|CLL1
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD33/CLL1 CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitleOptimized Dual CD33/CLL1 CAR T Cells in Subjects With Refractory or Relapsed Acute Myeloid Leukemia
Year2022
CountryChina
Company sponsorBeijing Boren Hospital
Other ID(s)BRYY-IIT-LCYJ-2021-026

Clinical Result

Cohort 1
Administration route None
Dosage 1E6 cells/kg (±20%), 5E6 cells/kg (±20%)
Pts 20
Age Child, Adult, Older_Adult
Lymph depletion Yes

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