Basic Information

Gene symbol KLRK1 Synonyms CD314, D12S2489E, KLR, NKG2-D, NKG2D Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description killer cell lectin like receptor K1

GTO ID GTC2940
Trial ID NCT05248048
Disease Colorectal Cancer
Altered gene NKG2D
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment NKG2D CAR-NK cells
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleNKG2D CAR-T Cells to Treat Patients With Previously Treated Liver Metastatic Colorectal Cancer
Year2022
CountryChina
Company sponsorThe Third Affiliated Hospital of Guangzhou Medical University
Other ID(s)CART-002

Clinical Result

Cohort 1
Administration route hepatic arterial infusion
Pts 9
Age Adult, Older_Adult

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