Basic Information

Gene symbol KLRK1 Synonyms CD314, D12S2489E, KLR, NKG2-D, NKG2D Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description killer cell lectin like receptor K1

GTO ID GTC2939
Trial ID NCT05247957
Disease Multiple Myeloma
Altered gene NKG2D
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment NKG2D CAR-NK cells
Recruitment statusTerminated
TitleNKG2D CAR-NK Cell Therapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia
Year2021
CountryChina
Company sponsorHangzhou Cheetah Cell Therapeutics Co., Ltd
Other ID(s)CARNK-001

Clinical Result

Cohort 1
Administration route None
Dosage 2E6 cells/kg, 6E6 cells/kg, 18E6 cells/kg
Pts 9
Age Child, Adult, Older_Adult
Lymph depletion Yes

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