Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC2921
Trial ID NCT05225831
Disease B-Cell Acute Lymphoblastic Leukemia
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD22 CAR-T cells
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleSafety and Efficacy of CD19/CD22 Dual Targeted CAR-T Cell Therapy in R/R B-Cell Acute Lymphoblastic Leukemia
Year2022
CountryChina
Company sponsorHebei Senlang Biotechnology Inc., Ltd.
Other ID(s)SL19+22 for B-ALL

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 100
Age Child, Adult, Older_Adult
Lymph depletion Yes

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