Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC2917
Trial ID NCT05223686
Disease Acute Lymphoblastic Leukemia
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD22 CAR-T cells
PhasePhase1
Recruitment statusNot Recruiting
TitleTo Evaluate the Safety and Tolerability of Human CD19-CD22 Targeted T Cells Injection for Subjects With R/R B-ALL.
Year2022
CountryChina
Company sponsorHrain Biotechnology Co., Ltd.
Other ID(s)HRAIN01-ALL02

Clinical Result

Cohort 1
Administration route None
Dosage 1E6 cells, 3E6 cells, 6E6 cells, Single infusion
Pts 18
Age Adult, Older_Adult
Lymph depletion Yes

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