Basic Information

Gene symbol GPRC5D Synonyms None Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description G protein-coupled receptor class C group 5 member D

GTO ID GTC2915
Trial ID NCT05219721
Disease Plasma Cell Leukemia | Multiple Myeloma
Altered gene GPRC5D
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CAR-GPRC5D
Generation2nd
PhasePhase1
Recruitment statusRecruiting
TitleA Study of CAR-GPRC5D in Patients With Relapsed/Refractory Multiple Myeloma or Plasma Cell Leukemia
Year2022
CountryChina
Company sponsorChunrui Li
Other ID(s)CAR-GPRC5DCI001

Clinical Result

Cohort 1
Administration route None
Dosage 0.5E6 cells/kg, 1E6 cells/kg, 2E6 cells/kg
Donor type Autologous
Pts 18
Age Adult, Older_Adult
Lymph depletion Yes

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