Gene symbol | KRAS | Synonyms | C-K-RAS, C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, K-Ras, K-Ras 2, KI-RAS, KRAS1, KRAS2, NS, NS3, OES, RALD, RASK2, c-Ki-ras, c-Ki-ras2 | Type of gene | protein-coding |
Chromosome | 12 | Map location | 12p12.1 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | KRAS proto-oncogene, GTPase |
GTO ID | GTC2902 |
Trial ID | NCT05202561 |
Disease | Advanced Solid Tumor |
Altered gene | KRAS |
Therapeutic/Target gene | Target gene |
Therapy | mRNA vaccine |
Treatment | RNA tumor Vaccine |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | A Single-Arm, Open-Label, Exploratory Study to Evaluate the Safety of RNA Tumor Vaccine Injection Alone/in Combination With PD-1 Inhibitor in the Treatment of Advanced Solid Tumors With KRAS Mutation |
Year | 2022 |
Country | China |
Company sponsor | First Affiliated Hospital Bengbu Medical College |
Other ID(s) | LWY21084CBY |
Cohort1: RNA tumor vaccine | |||||||||
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Cohort2: RNA tumor vaccine+Navuliumab | |||||||||
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