Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

GTO ID GTC2900
Trial ID NCT05201118
Disease Multiple Myeloma
Altered gene BCMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CT103A
Co-treatment Selinexor
Generation2nd
PhasePhase1
Recruitment statusRecruiting
TitleA Study of a Fully Human BCMA-targeting CAR (CT103A) Combined With Selinexor in Patients With Relapsed/Refractory Extramedullary Multiple Myeloma
Year2022
CountryChina
Company sponsorChunrui Li
Other ID(s)CAR CT103A SELINEXOR001
Vector information
Vectorlentivirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E6 cells/kg
Donor type Autologous
Pts 20
Age Adult, Older_Adult

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