Gene symbol | VEGFC | Synonyms | Flt4-L, LMPH1D, LMPHM4, VRP | Type of gene | protein-coding |
Chromosome | 4 | Map location | 4q34.3 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | vascular endothelial growth factor C |
GTO ID | GTC2896 |
Trial ID | NCT05197270 |
Disease | Age-Related Macular Degeneration |
Altered gene | VEGFC |
Therapeutic/Target gene | Target gene|Therapeutic gene |
Therapy | miRNA|mRNA |
Treatment | 4D-150 |
Phase | Phase1|Phase2 |
Recruitment status | Recruiting |
Title | A Phase 1/2 Dose-Escalation and Randomized, Controlled, Masked Expansion Trial of Intravitreal 4D-150 Gene Therapy in Adults With Neovascular (Wet) Age-Related Macular Degeneration |
Year | 2021 |
Country | United States|Puerto Rico |
Company sponsor | 4D Molecular Therapeutics |
Other ID(s) | 4D-150-C001 |
Vector information | |||||
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Cohort1: 4D-150 | |||||||||
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Cohort2: Aflibercept | |||||||||
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