Basic Information


GTO ID GTC2894
Trial ID NCT05195294
Disease Hepatocellular Carcinoma
Altered gene HBV gene
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment LioCyx-M
HLAHLA class I
PhasePhase1|Phase2
Recruitment statusNot Recruiting
TitleA Multi-center, Phase 1b/2 Study for Autologous T Cells Transfected With mRNA Encoding HBV Antigen-specific TCR (LioCyx-M) as Monotherapy or as Combination With Lenvatinib for Advanced HBV-related Hepatocellular Carcinoma
Year2021
CountrySingapore
Company sponsorLion TCR Pte. Ltd.
Other ID(s)LTCR-HCC-3-4

Clinical Result

Cohort1: LioCyx-M
Administration route infusion
Donor type autologous
Age Adult, Older_Adult
Lymph depletion No
Cohort2: LioCyx-M_Lenvatinib
Administration route infusion
Donor type autologous
Age Adult, Older_Adult
Lymph depletion No

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