Basic Information


GTO ID GTC2893
Trial ID NCT05194735
Disease Gynecologic Cancer | Colorectal Cancer | Pancreatic Cancer | Non-Small Cell Lung Cancer | Cholangiocarcinoma | Ovarian Cancer | Endometrial Cancer | Squamous Cell Lung Cancer
Altered gene Neoantigen
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment Neoantigen TCR-T cells
HLAHLA-A*11:01|HLA-C*08:02|HLA-C*01:02|HLA-A*02:01|HLA-DRB1*13:01|HLA-A*68:01|HLA-DRB3*02:02|HLA-DPA1*02:01|HLA-DPB1*01:01
PhasePhase1|Phase2
Recruitment statusActive, Not Recruiting
TitlePhase I/II Study of Autologous T Cells Engineered Using the Sleeping Beauty System to Express T-Cell Receptors (TCRs) Reactive Against Cancer-specific Mutations in Subjects With Solid Tumors
Year2022
CountryUnited States
Company sponsorAlaunos Therapeutics
Other ID(s)TCR001-201

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Pts 180
Age Adult, Older_Adult
Lymph depletion Yes

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