GTO ID | GTC2893 |
Trial ID | NCT05194735 |
Disease | Gynecologic Cancer | Colorectal Cancer | Pancreatic Cancer | Non-Small Cell Lung Cancer | Cholangiocarcinoma | Ovarian Cancer | Endometrial Cancer | Squamous Cell Lung Cancer |
Altered gene | Neoantigen |
Therapeutic/Target gene | Target gene |
Therapy | TCR-T cell |
Treatment | Neoantigen TCR-T cells |
HLA | HLA-A*11:01|HLA-C*08:02|HLA-C*01:02|HLA-A*02:01|HLA-DRB1*13:01|HLA-A*68:01|HLA-DRB3*02:02|HLA-DPA1*02:01|HLA-DPB1*01:01 |
Phase | Phase1|Phase2 |
Recruitment status | Active, Not Recruiting |
Title | Phase I/II Study of Autologous T Cells Engineered Using the Sleeping Beauty System to Express T-Cell Receptors (TCRs) Reactive Against Cancer-specific Mutations in Subjects With Solid Tumors |
Year | 2022 |
Country | United States |
Company sponsor | Alaunos Therapeutics |
Other ID(s) | TCR001-201 |
Cohort 1 | |||||||||||
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