Basic Information

Gene symbol TPBG Synonyms 5T4, 5T4AG, M6P1, WAIF1 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description trophoblast glycoprotein

GTO ID GTC2892
Trial ID NCT05194709
Disease Advanced Solid Tumor
Altered gene 5T4
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment 5T4 CAR-NK cells
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleStudy of Anti-5T4 CAR-NK Cell Therapy in Advanced Solid Tumors
Year2022
CountryChina
Company sponsorWuxi People's Hospital
Other ID(s)IBR854-T01|WX-IBR-8

Clinical Result

Cohort 1
Administration route None
Dosage 3E9 cells, 4E9 cells
Pts 40
Age Adult, Older_Adult
Lymph depletion No

Relationship Graph

Overview of Knowledge Graph