Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

GTO ID GTC2883
Trial ID NCT05181501
Disease Multiple Myeloma
Altered gene BCMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CT103A
Generation2nd
PhasePhase1
Recruitment statusNot Recruiting
TitleA Study of Fully Human BCMA CAR-T (CT103A) in Patients With Newly Diagnosed High-risk Multiple Myeloma (FUMANBA-2)
Year2022
CountryChina
Company sponsorNanjing IASO Biotherapeutics Co., Ltd
Other ID(s)CT103ACI001
Vector information
Vectorlentivirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E6 cells/kg, single infusion
Donor type Autologous
Pts 20
Age Adult, Older_Adult

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