Basic Information

Gene symbol CD7 Synonyms GP40, LEU-9, TP41, Tp40 Type of gene protein-coding
Description CD7 molecule

GTO ID GTC2881
Trial ID NCT05170568
Disease Non-Hodgkin's Lymphoma
Altered gene CD7
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment PA3-17
PhasePhase1
Recruitment statusRecruiting
TitlePA3-17 Injection Treatment of Adult Patients With CD7-positive Relapsed/Refractory Lymphoid Hematologic Malignancies
Year2021
CountryChina
Company sponsorPersonGen BioTherapeutics (Suzhou) Co., Ltd.
Other ID(s)PG-CART-07-001 (1)

Clinical Result

Cohort 1
Administration route None
Dosage 0.5E6 cells/kg, 2E6 cells/kg, 4E6 cells/kg
Donor type Autologous
Pts 9
Age Adult, Older_Adult
Outcome 7/9(CR)
Adverse reactions 7/9(CRS); 2/9(ICANS)
References DOI: 10.1182/blood-2023-178484

Relationship Graph

Overview of Knowledge Graph