Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC2879
Trial ID NCT05168748
Disease Acute Lymphoblastic Leukemia
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment IMJ995
PhasePhase1
Recruitment statusWithdrawn
TitleCD19- and CD22-directed CAR-T Cell Therapy in Patients With Acute Lymphoblastic Leukemia
Year2021
CountrySwitzerland
Company sponsorNovartis Pharmaceuticals
Other ID(s)CIMJ995A12101|2021-000677-89

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Pts 0
Age Child, Adult, Older_Adult

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