Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding | |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | Entrez:930 MIM:107265 HGNC:HGNC:1633 Ensembl:ENSG00000177455 AllianceGenome:HGNC:1633 | |
Description | CD19 molecule |
Gene symbol | CD22 | Synonyms | SIGLEC-2, SIGLEC2 | Type of gene | protein-coding | |
Chromosome | 19 | Map location | 19q13.12 | dbXrefs | Entrez:933 MIM:107266 HGNC:HGNC:1643 Ensembl:ENSG00000012124 AllianceGenome:HGNC:1643 | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | |||||
Description | CD22 molecule |
GTO ID | GTC2879 |
Trial ID | NCT05168748 |
Disease | Acute Lymphoblastic Leukemia |
Altered gene | CD19|CD22 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | IMJ995 |
Phase | Phase1 |
Recruitment status | Withdrawn |
Title | CD19- and CD22-directed CAR-T Cell Therapy in Patients With Acute Lymphoblastic Leukemia |
Year | 2021 |
Country | Switzerland |
Company sponsor | Novartis Pharmaceuticals |
Other ID(s) | CIMJ995A12101|2021-000677-89 |
Cohort 1 | |||||||||
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