Basic Information


GTO ID GTC2857
Trial ID NCT05140187
Disease CMV Infection
Altered gene CMV
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment CMV TCR-T cells
HLAHLA-A*02:01|HLA-A*24:02|HLA-A*11:01
PhasePhase1
Recruitment statusRecruiting
TitleAdoptive Immunotherapy With Donor-derived CMV-TCR-T Cells for Patients With CMV Infection After Allogenic HSCT
Year2021
CountryChina
Company sponsorChinese PLA General Hospital
Other ID(s)S2021-344-01
Vector information
Vectorlentivirus

Clinical Result

Cohort1: dose level 1
Administration route infusion
Dosage 1E3 cells/kg
Donor type Allogeneic
Age Child, Adult
Lymph depletion No
Cohort2: dose level 2
Administration route infusion
Dosage 1E5 cells/kg
Donor type Allogeneic
Age Child, Adult
Lymph depletion No
Cohort3: dose level 3
Administration route infusion
Dosage 5E5 cells/kg
Donor type Allogeneic
Age Child, Adult
Lymph depletion No

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