Basic Information

Gene symbol GPC3 Synonyms DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1 Type of gene protein-coding
Description glypican 3

GTO ID GTC2842
Trial ID NCT05120271
Disease Merkel Cell Carcinoma | Squamous Cell Carcinoma | Hepatocellular Carcinoma | Myxoid Liposarcoma
Altered gene GPC3
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment BOXR1030
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleBOXR1030 T Cells in Subjects With Advanced GPC3-Positive Solid Tumors
Year2021
CountryUnited States
Company sponsorSOTIO, LLC
Other ID(s)B1030-101

Clinical Result

Cohort 1
Administration route intravenous infusion
Pts 98
Age Adult, Older_Adult
Lymph depletion Yes
References : PMID: 35507536

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