Basic Information

Gene symbol S Synonyms E2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description spike glycoprotein

GTO ID GTC2841
Trial ID NCT05119855
Disease Coronavirus Infectious Disease | Human Papillomavirus Infectious Disease
Altered gene S
Therapeutic/Target gene Therapeutic gene
TherapymRNA vaccine
Treatment mRNA-1273|Elasomeran|Spikevax
Co-treatment 9vHPV Vaccine
Location approved UK, Canada, Taiwan, Switzerland, Japan, EU, Australia, South Korea, Singapore, US
PhasePhase3
Recruitment statusCompleted
TitleA Phase 3, Multicenter, Open-Label Study to Evaluate the Safety and Immunogenicity of 2-dose Regimens of 9vHPV and mRNA-1273 SARS-CoV-2 Vaccines Where the First Dose of Each Vaccine Are Given Concomitantly in Boys and Girls 9 to 11 Years of Age
Year2022
CountryUnited States
Company sponsorMerck Sharp & Dohme LLC
Other ID(s)V503-076|2021-003591-13
Vector information
Vectorlipid nanoparticle

Clinical Result

Cohort1: 9vHPV Vaccine_Day 1_Month 6
Administration route intramuscular injection
Dosage 50 mcg, Day 1, Month 1
Age Child
Cohort2: 9vHPV Vaccine_Day 2_Month 8
Administration route intramuscular injection
Dosage 50 mcg, Day 1, Month 1
Age Child

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