Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol MCAM Synonyms CD146, HEMCAM, METCAM, MUC18, MelCAM Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description melanoma cell adhesion molecule

GTO ID GTC2839
Trial ID NCT05117138
Disease Head and Neck Squamous Cell Carcinoma | Lung Non-Small Cell Carcinoma | Melanoma
Altered gene CD19|MUC18
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment AMT-116 CAR-T cells|AMT-253 CAR-T cells
PhasePhase1|Phase2
Recruitment statusNot Recruiting
TitleSafety and Efficacy of Chimeric Antigen Receptor T Lymphocytes for Patients With Intermediate and Advanced Tumors
Year2021
CountryChina
Company sponsorBeijing Immunochina Medical Science & Technology Co., Ltd.
Other ID(s)MHSW016

Clinical Result

Cohort1: NSCLC/HNSCC
Administration route None
Age Adult, Older_Adult
Cohort2: Melanoma
Administration route intravenous drip
Dosage 1E8 cells
Age Adult, Older_Adult

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