Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | MCAM | Synonyms | CD146, HEMCAM, METCAM, MUC18, MelCAM | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11q23.3 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | melanoma cell adhesion molecule |
GTO ID | GTC2839 |
Trial ID | NCT05117138 |
Disease | Head and Neck Squamous Cell Carcinoma | Lung Non-Small Cell Carcinoma | Melanoma |
Altered gene | CD19|MUC18 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | AMT-116 CAR-T cells|AMT-253 CAR-T cells |
Phase | Phase1|Phase2 |
Recruitment status | Not Recruiting |
Title | Safety and Efficacy of Chimeric Antigen Receptor T Lymphocytes for Patients With Intermediate and Advanced Tumors |
Year | 2021 |
Country | China |
Company sponsor | Beijing Immunochina Medical Science & Technology Co., Ltd. |
Other ID(s) | MHSW016 |
Cohort1: NSCLC/HNSCC | |||||||
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Cohort2: Melanoma | |||||||
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