Basic Information

Gene symbol CD5 Synonyms LEU1, T1 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD5 molecule

GTO ID GTC2837
Trial ID NCT05110742
Disease Hematologic Cancer
Altered gene CD5
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment CD5 CAR-NK cells
PhasePhase1|Phase2
Recruitment statusNot Recruiting
TitlePhase I/II Study of CD5 CAR Engineered IL15-Transduced Cord Blood-Derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapsed/Refractory Hematological Malignances
Year2021
CountryUnited States
Company sponsorM.D. Anderson Cancer Center
Other ID(s)2021-0526

Clinical Result

Cohort1: Phase 1
Administration route None
Dosage 1E7 cells, 1E8 cells, 1E9 cells, 1E10 cells
Age Adult, Older_Adult
Lymph depletion Yes
Cohort2: Phase 2
Administration route None
Age Adult, Older_Adult
Lymph depletion Yes

Relationship Graph

Overview of Knowledge Graph