Basic Information

Gene symbol VEGFA Synonyms L-VEGF, MVCD1, VEGF, VPF Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description vascular endothelial growth factor A

GTO ID GTC2829
Trial ID NCT05099094
Disease Retinal and Choroidal Neovascularization Disease
Altered gene VEGFA
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment BD311
PhasePhase1
Recruitment statusRecruiting
TitleA Safety and Efficacy Study of VEGFA-targeting Gene Therapy to Treat Refractory Retinal and Choroidal Neovascularization Diseases
Year2021
CountryChina
Company sponsorShanghai BDgene Co., Ltd.
Other ID(s)BD311
Vector information
Vectorlentivirus
Transgene/Inserted geneVEGFA antibody gene

Clinical Result

Cohort 1
Administration route suprachoroidal injection
Dosage 500uL
Age Adult, Older_Adult

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