Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC2828
Trial ID NCT05098613
Disease Non-Hodgkin's Lymphoma
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD22 CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitlePreliminary Safety and Tolerability of CD19x22 CAR T Cells in Adolescent and Adult R/R B-NHL Patients
Year2021
CountryUnited States
Company sponsorUniversity of Colorado, Denver
Other ID(s)21-2578.cc
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 20
Age Child, Adult, Older_Adult
Lymph depletion Yes

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