Basic Information

Gene symbol CD70 Synonyms CD27-L, CD27L, CD27LG, LPFS3, TNFSF7, TNLG8A Type of gene protein-coding
Description CD70 molecule

GTO ID GTC2824
Trial ID NCT05092451
Disease Myelodysplastic Syndrome | Acute Myeloid Leukemia | B-Cell Lymphoma
Altered gene CD70
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment CD70 CAR-NK cells
PhasePhase1|Phase2
Recruitment statusRecruiting
TitlePhase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances
Year2022
CountryUnited States
Company sponsorM.D. Anderson Cancer Center
Other ID(s)2021-0386|NCI-2021-12093

Clinical Result

Cohort 1
Administration route intravenous infusion
Pts 94
Age Adult, Older_Adult
Lymph depletion Yes

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