Gene symbol | CD70 | Synonyms | CD27-L, CD27L, CD27LG, LPFS3, TNFSF7, TNLG8A | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19p13.3 | dbXrefs | |
Description | CD70 molecule |
GTO ID | GTC2824 |
Trial ID | NCT05092451 |
Disease | Myelodysplastic Syndrome | Acute Myeloid Leukemia | B-Cell Lymphoma |
Altered gene | CD70 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-NK cell |
Treatment | CD70 CAR-NK cells |
Phase | Phase1|Phase2 |
Recruitment status | Recruiting |
Title | Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances |
Year | 2022 |
Country | United States |
Company sponsor | M.D. Anderson Cancer Center |
Other ID(s) | 2021-0386|NCI-2021-12093 |
Cohort 1 | |||||||||
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