Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC2823
Trial ID NCT05091541
Disease B-Cell Non-Hodgkin's Lymphoma
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CT120
PhasePhase1|Phase2
Recruitment statusNot Recruiting
TitleA Phase 1/2 Study of CT120 in Patient With Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma
Year2021
CountryChina
Company sponsorNanjing IASO Biotherapeutics Co., Ltd
Other ID(s)CT120C001
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route None
Dosage 1E6 cells/kg, 3E6 cells/kg, 6E6 cells/kg
Donor type Autologous
Pts 125
Age Adult, Older_Adult
Lymph depletion Yes

Relationship Graph

Overview of Knowledge Graph