Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC2814
Trial ID NCT05081479
Disease Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment YesCAR-Ta|Axicabtagene Ciloleucel|axi-cel
Co-treatment N-Acetylcysteine
Generation2nd
PhasePhase1
Recruitment statusRecruiting
TitleA Study of N-Acetylcysteine (N-AC)in People Receiving CAR T-cell Therapy for Lymphoma
Year2021
CountryUnited States
Company sponsorMemorial Sloan Kettering Cancer Center
Other ID(s)21-386
Vector information
Vectorlentivirus
ConstructscFv-CD28-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Pts 32
Age Adult, Older_Adult
Lymph depletion Yes

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