| Gene symbol | EGFR | Synonyms | ERBB, ERRP, HER1, mENA, ERBB1, PIG61, NISBD2 | Type of gene | protein-coding |
| Chromosome | 7 | Map location | 7p11.2 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
| Description | epidermal growth factor receptor | ||||
| GTO ID | GTC2798 |
| Trial ID | NCT05063682 |
| Disease | Brain Glioblastoma Multiforme | Glioblastoma | Malignant Glioma |
| Altered gene | EGFR |
| Therapeutic/Target gene | Target gene |
| Therapy | CAR-T cell |
| Treatment | EGFRvIII CAR-T cells |
| Generation | 2nd |
| Phase | Phase1 |
| Recruitment status | Active, Not Recruiting |
| Title | The Efficacy and Safety of Brain-targeting Immune Cells (EGFRvIII-CAR T Cells) in Treating Patients With Leptomeningeal Disease From Glioblastoma. Administering Patients EGFRvIII -CAR T Cells May Help to Recognize and Destroy Brain Tumor Cells in Patients |
| Year | 2021 |
| Country | India |
| Company sponsor | Chembrain LTD |
| Other ID(s) | 6678EGFRvIII |
| Cohort 1 | |||||||||||
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