Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
GTO ID | GTC2785 |
Trial ID | NCT05037669 |
Disease | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | Non-Hodgkin's Lymphoma |
Altered gene | CD19 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | PACE CAR-T19 |
Generation | 2nd |
Phase | Phase1 |
Recruitment status | Withdrawn |
Title | Programmed Allogeneic CRISPR-edited T Cells Engineered to Express Anti-CD19 Chimeric Antigen Receptor (PACE CART19) in Patients With Relapsed Or Refractory CD19+ Leukemia and Lymphoma |
Year | 2021 |
Country | United States |
Company sponsor | University of Pennsylvania |
Other ID(s) | UPCC 27419 |
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