Basic Information

Gene symbol EPCAM Synonyms Ber-Ep4, BerEp4, DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, LYNCH8, M4S1, MIC18, MK-1, MOC-31, TACSTD1, TROP1 Type of gene protein-coding
Description epithelial cell adhesion molecule

GTO ID GTC2777
Trial ID NCT05028933
Disease Pancreatic Cancer | Hepatocellular Carcinoma | Colorectal Cancer | Stomach Cancer
Altered gene EpCAM
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment EpCAM CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitleIMC001 for Clinical Research on Advanced Digestive System Malignancies
Year2021
CountryChina
Company sponsorZhejiang University
Other ID(s)IMC001-CT04

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 3E5 cells/kg (±10%), 1E6 cells/kg (±10%), 3E6 cells/kg (±10%)
Donor type Autologous
Pts 48
Age Adult, Older_Adult

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