Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC2771
Trial ID NCT05020392
Disease Diffuse Large B-Cell Lymphoma | Chronic Lymphocytic Leukemia | Follicular Lymphoma | Burkitt Lymphoma | Mantle Cell Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CAR-T cells
Co-treatment BTK inhibitor
PhasePhase3
Recruitment statusRecruiting
TitleAutologous Cells Derived Anti-CD19 CAR-Engineered T Cells With Concurrent BTK Inhibitor for B Cell Lymphoma
Year2021
CountryChina
Company sponsorWuhan Union Hospital, China
Other ID(s)auto-CART-CD19 cells and BTKi
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route None
Dosage 1E6 cells/kg
Donor type Autologous
Pts 24
Age Adult, Older_Adult
Lymph depletion Yes

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