Basic Information

Gene symbol CD33 Synonyms CD33rSiglec, SIGLEC-3, SIGLEC3, p67 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD33 molecule

Gene symbol COLEC10 Synonyms 3MC3, CL-10, CL-34, CLL1 Type of gene protein-coding
Description collectin subfamily member 10

GTO ID GTC2764
Trial ID NCT05016063
Disease Acute Myeloid Leukemia
Altered gene CD33|CLL1
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD33/CLL1 CAR-T cells
PhaseEarly_Phase1
Recruitment statusNot Recruiting
TitleDual CD33-CLL1-CAR-T Cells in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia
Year2021
CountryChina
Company sponsorXinqiao Hospital of Chongqing
Other ID(s)Dual CD33-CLL1 CAR-T cells

Clinical Result

Cohort 1
Administration route None
Dosage 0.5E6 cells/kg
Pts 32
Age Adult, Older_Adult
Lymph depletion Yes

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