Basic Information

Gene symbol CD33 Synonyms CD33rSiglec, SIGLEC-3, SIGLEC3, p67 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD33 molecule

GTO ID GTC2757
Trial ID NCT05008575
Disease Acute Myeloid Leukemia
Altered gene CD33
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment CD33 CAR-NK cells
PhasePhase1
Recruitment statusUnknown
TitleAnti-CD33 CAR NK Cells in the Treatment of Relapsed/Refractory Acute Myeloid Leukemia
Year2021
CountryChina
Company sponsorXinqiao Hospital of Chongqing

Clinical Result

Cohort 1
Administration route None
Dosage 6E8 cells/kg, 12E8 cells/kg, 18E8 cells/kg
Pts 27
Age Adult, Older_Adult
Lymph depletion Yes

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