Basic Information

Gene symbol GPC3 Synonyms DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1 Type of gene protein-coding
Description glypican 3

GTO ID GTC2754
Trial ID NCT05003895
Disease Hepatocellular Carcinoma
Altered gene GPC3
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment GPC3 CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitleGPC3 Targeted CAR-T Cell Therapy in Advanced GPC3 Expressing Hepatocellular Carcinoma (HCC)
Year2021
CountryUnited States
Company sponsorNational Cancer Institute (NCI)
Other ID(s)210030|21-C-0030

Clinical Result

Cohort 1
Administration route None
Pts 38
Age Adult, Older_Adult
Lymph depletion Yes

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